John R Cashman Selected Research

dimethylaniline monooxygenase (N-oxide forming) (flavin-containing monooxygenase)

6/2009	Novel variants of the human flavin-containing monooxygenase 3 (FMO3) gene associated with trimethylaminuria.
3/2009	Hepatic flavin-containing monooxygenase gene regulation in different mouse inflammation models.
4/2008	Analysis of flavin-containing monooxygenase 3 genotype data in populations administered the anti-schizophrenia agent olanzapine.
12/2007	Flavin-containing monooxygenase 3 and human disease.
1/2007	Transient trimethylaminuria related to menstruation.
1/2007	Stop codon mutations in the flavin-containing monooxygenase 3 (FMO3) gene responsible for trimethylaminuria in a Japanese population.
8/2003	Deleterious mutations in the flavin-containing monooxygenase 3 (FMO3) gene causing trimethylaminuria.
4/2003	Biochemical and clinical aspects of the human flavin-containing monooxygenase form 3 (FMO3) related to trimethylaminuria.
10/2002	Interindividual differences of human flavin-containing monooxygenase 3: genetic polymorphisms and functional variation.

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John R Cashman Research Topics

Disease

9	Trimethylaminuria 06/2009 - 05/2002
8	Neoplasms (Cancer) 01/2021 - 01/2005
4	Poisoning 12/2020 - 04/2010
3	Alzheimer Disease (Alzheimer's Disease) 01/2018 - 08/2008
2	Pancreatic Neoplasms (Pancreatic Cancer) 01/2021 - 01/2020
2	Inflammation (Inflammations) 03/2010 - 03/2009
1	Long QT Syndrome 01/2021
1	Long QT syndrome type 3 01/2021
1	Heart Diseases (Heart Disease) 11/2020
1	Long Qt Syndrome 3 11/2020
1	Neoplasm Metastasis (Metastasis) 01/2020
1	Prostatic Neoplasms (Prostate Cancer) 12/2019
1	Breast Neoplasms (Breast Cancer) 01/2018
1	Colonic Neoplasms (Colon Cancer) 01/2018
1	Dementia (Dementias) 01/2018
1	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2018
1	Colorectal Neoplasms (Colorectal Cancer) 01/2018
1	Congenital Heart Defects (Congenital Heart Defect) 01/2017
1	Cardiac Arrhythmias (Arrythmia) 01/2017
1	Colitis 03/2009
1	Amyloidosis 12/2008
1	Weight Gain 04/2008
1	Hallucinations (Hallucination) 04/2008
1	Schizophrenia (Dementia Praecox) 04/2008
1	Inborn Genetic Diseases (Disease, Hereditary) 12/2007
1	Pain (Aches) 01/2005
1	Vomiting 01/2005
1	Nausea 01/2005
1	Respiratory Insufficiency (Respiratory Failure) 01/2005
1	Lung Neoplasms (Lung Cancer) 08/2003
1	Body Odor 04/2003
1	Hypertension (High Blood Pressure) 04/2003

Drug/Important Bio-Agent (IBA)

9	dimethylaniline monooxygenase (N-oxide forming) (flavin-containing monooxygenase)IBA 06/2009 - 10/2002
7	Pharmaceutical PreparationsIBA 01/2021 - 04/2003
5	trimethylamineIBA 01/2007 - 05/2002
3	Proteins (Proteins, Gene)FDA Link 01/2021 - 04/2010
3	PAWI-2IBA 01/2021 - 12/2019
2	Mexiletine (Mexitil)FDA LinkGeneric 01/2021 - 11/2020
2	Sodium Channels (Sodium Channel)IBA 01/2021 - 11/2020
2	Biomarkers (Surrogate Marker)IBA 01/2021 - 12/2020
2	Amyloid beta-PeptidesIBA 01/2018 - 12/2008
2	Nerve AgentsIBA 03/2011 - 04/2010
2	EnzymesIBA 04/2010 - 01/2010
2	trimethyloxamine (trimethylamine N-oxide)IBA 04/2004 - 04/2003
1	AntibodiesIBA 12/2020
1	ButyrylcholinesteraseIBA 12/2020
1	Sepharose (Agarose)IBA 12/2020
1	Anti-Arrhythmia AgentsIBA 11/2020
1	IntegrinsIBA 01/2020
1	enzalutamideIBA 12/2019
1	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2018
1	CurcuminIBA 01/2018
1	CateninsIBA 01/2018
1	SulfonamidesIBA 01/2018
1	Calcitriol Receptors (Calcitriol Receptor)IBA 01/2012
1	Amyloid (Amyloid Fibrils)IBA 01/2012
1	OximesIBA 05/2011
1	Carboxylesterase (Hydrolase S)IBA 04/2010
1	Cholinesterases (Cholinesterase)IBA 04/2010
1	NF-kappa B (NF-kB)IBA 03/2010
1	Antigen Receptors (Antigen Receptor)IBA 03/2010
1	Biological ProductsIBA 01/2010
1	Messenger RNA (mRNA)IBA 03/2009
1	Cytochrome P-450 Enzyme System (Cytochrome P450)IBA 03/2009
1	Mixed Function Oxygenases (Monooxygenases)IBA 03/2009
1	LipopolysaccharidesIBA 03/2009
1	4,6-dinitro-o-cresol (DNOC)IBA 03/2009
1	Dextran SulfateIBA 03/2009
1	Protein Isoforms (Isoforms)IBA 03/2009
1	piperineIBA 08/2008
1	DiarylheptanoidsIBA 08/2008
1	Olanzapine (Zyprexa)FDA Link 04/2008
1	DNA (Deoxyribonucleic Acid)IBA 01/2007
1	Codon (Codons)IBA 01/2007
1	Analgesics (Analgesic Drugs)IBA 01/2005
1	morphine-6-glucuronideIBA 01/2005
1	Morphine (MS Contin)FDA LinkGeneric 01/2005
1	Opioid Analgesics (Opioids)IBA 01/2005
1	Charcoal (Charbon)IBA 04/2004
1	chlorophyllin (copper chlorophyll)IBA 04/2004
1	SmokeIBA 08/2003
1	Choline (Choline Chloride)IBA 04/2003
1	VitaminsIBA 04/2003

Therapy/Procedure

6	Therapeutics 01/2021 - 11/2010
2	Drug Therapy (Chemotherapy) 12/2019 - 01/2018
1	Castration 12/2019
1	Analgesia 01/2005
1	Total Parenteral Nutrition 02/2004
1	Nutritional Support (Artificial Feeding) 04/2003